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Plants Extract
Baicalein
| Chemical Properties | Yellow Crystalline Solid |
| Uses | antiviral (HIV) |
| Uses | An inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. Baicalein is the fl avonoid component of Nepalese and Sino-Japanese crude drugs. |
| Uses | inhibitor of lipoxidase and leukotriene biosynthesis |
| Uses | An inhibitor of Ca2+ uptake, 5-LO, and 12-LO |
| Biological Activity | Inhibitor of 5- and platelet 12-lipoxygenases (IC 50 values are 9.5 and 0.12 mM respectively). Also inhibits Raf-mediated MEK-1 phosphorylation in C6 rat glioma cells and induces G1 and G2 cell cycle arrest by decreasing cdk1, cdk2, cyclin D2 and cyclin A expression. Anti-inflammatory in vivo . |
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